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CT analysis of tumour bearing bones showed significantly inc
2019-06-12
μCT analysis of tumour bearing bones showed significantly increased bone density in animals receiving zoledronic acid, alone or in combination with doxorubicin, compared to PBS control. Our results confirmed that a single dose of zoledronic abscisic acid caused sustained bone effects throughout the
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More recently primary tumor driven generation of a
2019-06-12
More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i
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br Material and methods br
2019-06-12
Material and methods Results Discussion PV isolation is currently the cornerstone for treatment of patients with paroxysmal AF [6]. An extended technique is circumferential PV isolation using point-by-point ablation around the PV ostium. However, that is a technically challenging and time-c
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Heat shock facilitates the folding of various proteins
2019-06-12
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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The IntellaTip Mifi catheter has been shown to delineate
2019-06-12
The IntellaTip Mifi catheter has been shown to delineate local electograms better in the isthmus than the conventional bipolar electrode during atrial flutter ablation. The signal amplitude in the mini-electrodes has been noted to be higher than that of the conventional bipolar catheter. This has en
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Pregnancies in adolescents year olds and in
2019-06-12
Pregnancies in adolescents (10–19-year-olds) and in older women (≥35 years) are hazardous for the mother and the child. Despite an almost universal decline in the adolescent LJI308 Supplier since 1990, adolescent fertility still accounts for 11% of all births worldwide, with 95% of these births occ
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Cardiac troponin I cTnI is
2019-06-11
Cardiac troponin I (cTnI) is a well-established, sensitive, and specific marker of myocardial injury. However, evidence indicates that unrecognized myocardial injury may be occurring with certain conditions such as sepsis without acute coronary ischemic event, which demonstrate elevated cTnI levels.
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De todas maneras no escapa a la tem
2019-06-11
De todas maneras no escapa a la temática de este trabajo la intuición de un contradictorio hecho: de que en este intento de interpretación de estos dos polémicos capítulos de Paradiso, dionisíacos, lo que estamos haciendo es, una vez más, buscar la sistematización iluminista, apolínea, a la que el m
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Introduction Classically increased cardiac fibrosis has been
2019-06-11
Introduction Classically, increased cardiac fibrosis has been shown to be associated with altered cardiac conduction, causing conduction slowing, block, and reentry in studies on isolated animal and diseased human cardiac tissues [1–3]. Interestingly, similar findings were also demonstrated in isol
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It was imperative to make patients a first priority who
2019-06-11
It was imperative to make patients a first priority who had a definitive diagnosis needing immediate, timely, and effective interventions, including primary coronary intervention (PCI), permanent polo like kinase implantation, and were most likely to be admitted to CCU postprocedurally (Table 1). In
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br Escribir y destacar promoci n la identidad por
2019-06-11
Escribir y destacar (promoción 1975-1985): la identidad por las diferencias ¿Cómo escribir dentro de un mercado de tantos competidores para un país de escasos lectores? En México, ni siquiera los estudiantes de la universidad consumen libros y hay más papelerías que librerías (Zaid 2013: 143-154
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It is good to see any cluster randomised
2019-06-11
It is good to see any cluster-randomised order Erlotinib Hydrochloride trial of a handwashing intervention, much more a successful one. Globally there is considerable funding invested in handwashing promotion, yet the kind of rigorous study published in this month\'s issue of by Adam Biran and col
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Antenatal corticosteroids induce fetal lung maturation
2019-06-11
Antenatal corticosteroids induce fetal lung maturation through the same biological mechanism in low-income settings as in high-income settings and reduce the need for neonatal mechanical ventilation. Although antenatal corticosteroids might not be a so-called magic bullet as a standalone vertical in
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br CUANDO EL CUERPO SE HACE
2019-06-11
CUANDO EL CUERPO SE HACE ESPACIO El punto en común de estos lienzos es la ausencia de mirada (figuras 3a y 3b). En el primero los ojos están negros, se presentan las dos órbitas vacías; en el segundo están deliberadamente borrados, ya que incluso se puede distinguir por debajo el contorno de los
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Esta parte de la cr tica a la
2019-06-11
Esta parte de la crítica a la que aludo, en aquel entonces, se orienta hacia el replanteamiento de la función social de la literatura y el cuestionamiento epistemológico de la práctica crítica misma. Incidiendo en este aspecto, George Gugelberger llega a afirmar lo siguiente: “Thus, the testimonio b
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