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The treatment of TEN poses a great challenge because
2018-11-06
The treatment of TEN poses a great challenge because of the rapid onset and progression of daunorubicin exfoliation with sepsis. Unfortunately, even with the advances in modern medicine, including improvements in intensive care, development of new dressing material and systemic therapies such as glu
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Tanaka and his team were
2018-11-06
Tanaka and his team were also focused on the chemical examination of theasinensin production using in vitro experiments to mimic black tea production process in particular on the fermentation step. EGCG and cholinesterase inhibitors from homogeneous pear were applied at room temperature for 2h. The
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As shown in Table the
2018-11-06
As shown in Table 3, the extract also inhibited Fe2+-induced lipid peroxidation in the kidney, liver and lungs tissues homogenates of rats. Its IC50 values varied significantly (Plungs (26.65±1.82μg/mL)>kidney (20.39±1.19μg/mL); and its pattern of inhibition was also dose-dependent as shown in Fig.
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The following are the supplementary data related
2018-11-06
The following are the supplementary data related to this article. Introduction Acute kidney injury (AKI), which is characterized by impaired renal function, results in a major clinical problem especially in critically ill patients admitted to the intensive care unit. Considering the poor outcome
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Unfortunately existing cytogenetic karyotyping methods are l
2018-11-06
Unfortunately, existing cytogenetic karyotyping methods are labor intensive, requiring at least 15 fixed metaphase preparations, subsequent DAPI staining, and analysis with an epi-fluorescence microscope equipped with specialized digital imaging software. Conventional karyotyping is expensive (∼$400
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br Materials and methods br Results br Discussion Recent neu
2018-11-06
Materials and methods Results Discussion Recent neurogenesis studies and the discovery of multipotent neural stem nobiletin derived from the adult mammalian CNS, including that of humans, have had a considerable influence on potential treatments for neural injury (Gross, 2000; Ming and Son
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While M macrophages may be the principal drivers of angiogen
2018-11-06
While M2 macrophages may be the principal drivers of angiogenesis associated with injury resolution, M1 macrophages are highly fibrolytic, which may facilitate angiogenesis, and secrete pro-angiogenic factors such as TNFα and IL-1β, and nitric oxide (Sunderkotter et al., 1994; Cooke & Losordo, 2002)
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Mesenchymal stem cells MSCs can be isolated from
2018-11-06
Mesenchymal stem DMXAA (MSCs) can be isolated from various adult tissues (including bone marrow), they are multipotent and can differentiate into cells of the mesodermal (e.g. adipocytes, osteocytes, chondrocytes) as well as other embryonic lineages (Jiang et al., 2002). MSCs can also be cultured i
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SDCs and GPCs have been reported to
2018-11-06
SDCs and GPCs have been reported to regulate cell adhesion, migration and differentiation and demonstrate specific expression and localisation during CNS development (Choi et al., 2011, Ford-Perriss et al., 2003). The depletion of SDC1, GPC1 and GPC4 in vitro in mouse NSC or neural precursor cells a
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DNA fingerprinting confirmed the genetic relation
2018-11-06
DNA fingerprinting confirmed the genetic relation of the derivative line to the parental somatic line (Fig. 1B). The JQ1 exhibited normal karyotype (46, XY) upon G-band analysis (Fig. 1C). Pluripotency was verified by gene expression of pluripotent stem cell markers Oct4, Sox2, Nanog, Rex1, DMNT3B
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Fortunately a new class of RNA guided nucleases has
2018-11-06
Fortunately, a new class of RNA-guided nucleases has been developed from microbial adaptive immune systems (i.e. clustered regularly interspaced short palindromic repeat-CRISPR- and CRISPR associated Cas9-CRISPR/Cas9-systems) (Cong et al., 2013; Mali et al., 2013a). This system provides a very simpl
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The leading approaches to this are DA cell transplantation
2018-11-06
The leading approaches to this are DA cell transplantation, or stimulating endogenous DA neurogenesis, in either SNc or its efferent target the dorsal striatum. Despite progression of cell transplantation to clinical trials, it is still not widely available due to lack of a standardized and morally
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While the lack of terminal differentiation and ectopic ventr
2018-11-05
While the lack of terminal differentiation and ectopic ventricular clusters became a major focus of our investigation, we were similarly surprised by the lack of cognitive improvement following HuCNS-SC transplantation. We have previously found that NSC-derived BDNF can play a critical role in stem
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Sapitinib There is increasing evidence that in a
2018-11-05
There is increasing evidence that in a variety of neoplasia, including breast cancer, only a subset of cancer Sapitinib are capable of reconstituting the tumor after transplantation. These cells called cancer stem cells (CSCs) or tumor-initiating cells (TICs), have the ability to self-renew and reg
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Introduction The first studies on tomographic imaging were
2018-11-05
Introduction The first studies on tomographic imaging were dedicated to solving a number of medical problems and appeared in the 1960s. At that time the principal source of analyzed information was the data obtained when measuring the level of radiation absorbed by an object in the X-ray wavelength
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