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In this study we found that
2018-10-20
In this study, we found that while zebrafish med14 mutant embryos were largely arrested in development, there was a surprisingly limited effect on overall transcription. Transplantation experiments demonstrated that Med14 function is largely dispensable for cell survival into adulthood. Loss of med1
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Acute and transient MF activation
2018-10-20
Acute and transient MF activation is part of the body’s normal wound healing program, but persistent MFs contribute to fibrosis by excessively producing and contracting collagenous extracellular matrix (ECM) into stiff scar tissue (Hinz et al., 2012). In turn, the stiffness of mature scar promotes m
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The inhibition of differentiation has been considered to pla
2018-10-20
The inhibition of differentiation has been considered to play a role in many types of tumor development through maintenance of the proliferating progenitor cell state. Previous studies demonstrated that the knockdown of EWS-FLI1 in Ewing sarcoma cell lines results in osteogenic, adipogenic and chond
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br Experimental Procedures See Supplemental Experimental Pro
2018-10-20
Experimental Procedures See Supplemental Experimental Procedures for details on mice, flow cytometry and cell sorting, cell-cycle and apoptosis analysis, myeloid progenitor and Lys-GFP in vitro differentiation assay, and gene expression. Author Contributions Acknowledgments Introduction
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Whether LIF contributes to differentiation inhibition in rab
2018-10-20
Whether LIF contributes to differentiation inhibition in rabbit PSCs is unclear. LIF and FGF2 cooperatively support self-renewal in ESCs derived from parthenogenotes and propagated in feeder-free conditions, but the effect of LIF is modest (Hsieh et al., 2011). In this study, AKSL and AKSgff cell li
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Hello world!
2018-07-29
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