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Besides the production of transgenic
2018-11-12
Besides the production of transgenic spermatozoa and animal production, studies using in vitro maintained spermatogonial stem antibiotics are important to identify the mechanism of spermatogenesis in mammals, facilitate research on male infertility, and disseminate the genetics of animal production.
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ES cells which have been used
2018-11-12
ES cells, which have been used frequently for research in the field of developmental biology and tried to apply in cell-based regenerative medicine (Murry and Keller, 2008), replicate by the process of self-renewal and several different pathways are believed to be involved in the regulation of self-
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Introduction Mechanical loading of cells
2018-11-12
Introduction Mechanical loading of order DMOG and tissues by gravity-generated forces has broad effects on mammalian cell and tissue physiology, such as in promoting the normal function and regeneration of bone, muscle, blood, and other tissues. In a healthy organism, many cell types, including os
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br Materials and methods br
2018-11-12
Materials and methods Results and discussion Acknowledgments Introduction Reprogramming rejuvenates aged somatic cells back into the pluripotent state (Takahashi et al., 2007; Takahashi and Yamanaka, 2006). The developmental plasticity of induced pluripotent stem cells (iPSC) demonstrate
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br Experimental Procedures br Author Contributions br Acknow
2018-11-09
Experimental Procedures Author Contributions Acknowledgments Our thanks go to Gioia Polidori Francisco for training and discussions, Kate Watt and Yvonne Turnbull for technical and laboratory managerial support, Kadri Oras and Laura Ferguson for experimental support, Po-Lin So and Bruce Con
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To show seasonality of VC over a year decade averages
2018-11-09
To show seasonality of VC over a year, decade averages of VC for each month was displayed as a function of the month in a year. For the recent decade, 13 cities were chosen to compare seasonality of DEP. Ten European cities were selected to represent most of the European continent with different tem
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cetrimonium bromide Lung cancer is the most common cancer in
2018-11-09
Lung cancer is the most common cancer in US and worldwide (Centers for Disease Control and Prevention and National Center for Health Statistics, 2013; American Cancer Society, 2014), and the survival rate is low (Howlader et al., 2013). Most cases (90%) of lung cancer are attributable to smoking (Ge
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Remarkable progress has been made in the treatment of
2018-11-09
Remarkable progress has been made in the treatment of ALL. Currently, the five-year overall survival rates exceed 85% in pediatric patients in developed countries (Pui et al., 2015), but remain less than 45% in adults (Jabbour et al., 2015; Bassan and Hoelzer, 2011).The poor outcome in adults has be
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It is technically challenging to
2018-11-09
It is technically challenging to extract proteins of interest from bone due to the abundance of collagens and minerals. A pilot study using HCl/Urea extraction identified 119 proteins in OA subchondral bone with only 7 proteins shared between the low and high damage regions. This data suggests that
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We also examined Smad as an
2018-11-09
We also examined Smad7 as an important regulator of the TGF-β signaling pathway as it inhibits phosphorylation of Smad2 by the TGF-β receptors, thereby acting as a negative feedback loop in this pathway to prevent deregulation. Without Smad7, TGF-β receptor activation cannot be inhibited -explaining
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The second major criticism of covariate adaptive methods
2018-11-09
The second major criticism of covariate-adaptive methods is that balancing can complicate inference. In our view, this concern is overstated because many simulation studies have shown that simply controlling for balancing covariates is sufficient for conservative inference in most cases. In addition
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To combat these challenges a government initiative in distri
2018-11-09
To combat these challenges, a government initiative in 2012 distributed a two burner liquefied petroleum gas (LPG) stove and one tank of gas to each household, but these stoves go largely unused today due to the relatively high cost of LPG (Partnerships, 2012). Most residents in the rural villages c
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br Conflict of interest statement br
2018-11-09
Conflict of interest statement Acknowledgements We acknowledge support from the National Institute on Drug Abuse, NIH (R21DA022546-01), and the National Institute on Alcohol Abuse and Alcoholism, NIH (R01AA020006-01). We also thank the research assistants and students who helped complete this
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EZ Cap Reagent AG (3\' OMe) br Neuroimmune mechanisms un
2018-11-09
Neuroimmune mechanisms underlying sex differences Measuring developmental and life-long effects of ELA exposure produces a moving baseline from which to gauge anatomical and functional differences. Therefore the addition of sex as a factor in developmental studies is challenging. While some anima
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br Methods br Results br Discussion The
2018-11-09
Methods Results Discussion The notion of trait hypoactivation in right aTPJ is intriguing given the temporoparietal junction\'s well-established roles in both social and attentional processes (for reviews see Carter and Huettel, 2013; Decety and Lamm, 2007). Due to the social nature of the
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