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br Discussion Firstly we find that
2018-11-05
Discussion Firstly, we find that activation of GSK-3β in peripheral circulating platelet is diagnostic of cognitive impairment in T2DM patients. Accumulating laboratory evidence suggest that GSK-3β activation is involved in both T2DM and AD, such as disturbed glycogen metabolism (Rayasam et al.,
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The gene was cloned in and
2018-11-05
The gene was cloned in 1990 and initial studies of the large complex gene identified only between 30 and 65% of germline mutations in clearly affected individuals (Shen et al., 1996). Furthermore, phenotype analysis in pedigrees suggested that there would be little significant genotype–phenotype cor
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The combination of romidepsin and bryostatin has
2018-11-05
The combination of romidepsin and bryostatin-1 has been shown to be one of the best inducers of latent HIV-1 in primary CD4+ T orphan receptor (Laird et al., 2015). However, bryostatin-1 has been showed to be involved in the modulation of NFkB and NFAT (Williams et al., 2004) and romidepsin is know
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A striking challenge in studying Alzheimer s
2018-11-05
A striking challenge in studying Alzheimer\'s disease is the use of appropriate animal models. Since Aβ peptides derived from murine APP do not lead to neurodegeneration, almost all animal studies are based on humanized mice overexpressing human APP. Moreover, the mutated APP variant inserted in the
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DMH-1 One of the interesting aspects of the findings in this
2018-11-05
One of the interesting aspects of the findings in this study is the dissociation between the large phase advances/delays observed in the biochemical rhythms and the much more moderate changes in the sleep/wake cycle. We believe that this discrepancy mainly derives from the environmental/behavioral c
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Celecoxib Norway Funding by the Norwegian Cancer Society and
2018-11-05
Norway: Funding by the Norwegian Cancer Society and the Norwegian Research Council. The Resource for Lung Cancer in North Trent (ReSoLUCENT)/Sheffield: This study has been supported by Sheffield ECMC (Experimental Cancer Medicine Centre) and Weston Park Hospital Cancer Charity. Tampa, FL: This stu
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cdc42 pathway br Funding Sources Research reported in this p
2018-11-05
Funding Sources Research reported in this publication was supported by a grant from the Canadian Institutes for Health ResearchMOP-74493, the National Institute of Allergy and Infectious Diseases (NIAID) of the U. S. National Institutes of Health under Award Number R33AI098701, and the Intramural
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br Methods br Results br
2018-11-05
Methods Results Discussion The intriguing relationship between commensal microbes and atherosclerosis has received increasing attention over the past few years. However, the specific mechanisms whereby commensal microbes regulate the development of atherosclerosis are just beginning to be e
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Harman and Stewardson mentioned that only a few published
2018-11-05
Harman and Stewardson (2005) mentioned that only a few published studies explicitly described the link between environmental flow targets and dam operating rules. To resolve the river management-driven issues and bridge the gap between a simple minimum stream flow target and the great complexity of
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In fact reducing the production
2018-11-05
In fact, reducing the production cost of CNTs growth in large-scale requires quantitative and qualitative optimization studies of CVD parametric effects on CNTs growth, a concept which has not been fully developed. The present work is an optimization study of synthesis parameters involved in carbon
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br Case report A year old boy
2018-11-05
Case report A 15-year-old boy complaining of unexplained fatigue was first attended by the pediatrics office on November 2010. Such discomfort started in June, two months after being vaccinated against the 2009 pandemic influenza A/H1N1 virus with Pandemrix™. Physical and neurological examination
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To assess the hypothesis neuronal elements presumably affect
2018-11-05
To assess the hypothesis, neuronal elements presumably affecting early daily habits and successful life are reviewed. As such neuronal elements, 5-HT, oxytocin, the PFC and the ventral/dorsal striatum were selected with reference to previous studies [9]. Relationships among these elements are shown
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br Experimental br Result and discussions br Integration of
2018-11-05
Experimental Result and discussions Integration of the FIA-ET biosensor with android platform Facilitation of decision support system Decision support system is provided for data analysis. Android application is pre-programmed for decision making. Where necessary, computations are made w
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br Funding This work was funded by
2018-11-03
Funding This work was funded by the National Institutes of Health (NIH)/National Institute of Allergy and Infectious Diseases (NIAID) contract HHSN272200800047C to EP. The Kawempe Community Health Study was funded entirely by the Tuberculosis Research Unit (grant N01-AI95383 and HHSN266200700022C
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br Experimental design materials and methods
2018-11-03
Experimental design, materials and methods Conflict of interest Acknowledgments The work is supported by the Faculty Research Fund (FRG1/13–14/010; BIOL3840101) to WKFT and General Research Fund (261610), Research Grant Council Hong Kong to CKCW. Experimental design, materials and method
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