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Our results showed suppressed autophagy in
2024-01-08
Our results showed suppressed autophagy in GECs under HAGG stimulation. Recently, people have paid more attentions on the roles of autophagy in lupus and tried to use autophagy regulators for therapy. Rapamycin could prevent the development of nephritis [49] and attenuate the established nephritis [
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71 5 Finally not only can ERs pair with different
2024-01-08
Finally, not only can ERs pair with different mGluRs in different 71 5 regions, but it is becoming increasingly clear that the same mGluRs can pair with distinct downstream signaling partners to have differential effects both within and across brain regions (Gross et al., 2016; Mannaioni et al., 20
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The use of FTAI can overcome
2024-01-08
The use of FTAI can overcome the negative impact of low estrus detection efficiency, but implies effective synchrony of luteal function as well as synchronous growth and ovulation of a viable ro bio 2 follicle. Pregnancy rates obtained with FTAI may be comparable or better than those obtained after
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Apelin is involved in various physiological
2024-01-08
Apelin is involved in various physiological functions, including Superoxide Dismutase (SOD) Activity Assay Kit sale contraction (Ashley et al., 2005), vasodilatation (Jia et al., 2007), feeding control (Valle et al., 2008), and metabolic homeostasis (Higuchi et al., 2007, Dray et al., 2008, Attane
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br Conclusions In summary we report a novel
2024-01-08
Conclusions In summary, we report a novel preliminary finding of a potential racial difference in the association of Cd-content and AR expression in prostate cancer that will need to be confirmed in larger studies. Although the association of Cd and AR protein expression is not strong in tumor ti
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br The prevalence of diabetes
2024-01-08
The prevalence of diabetes is increasing globally, and the situation is particularly alarming in Asia. The prevalence of diabetes in China has increased dramatically, from around 1% in 1980 to the most recent estimate of 9.7% according to a nationwide survey . Cumulative evidence shows that type 2
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In view of the ubiquitous distribution of the arachidonate
2024-01-05
In view of the ubiquitous distribution of the arachidonate 12S-lipoxygenase isoforms and the variety of cellular reactions influenced by the resulting arachidonate metabolites, these products widely play important roles in many biological systems. The development of new type-specific inhibitors of t
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Blocking the action of CREB with
2024-01-05
Blocking the action of CREB with the C646 inhibitor together with increasing Akt activation with the SC79 agonist is particularly interesting as it significantly reduced wound closure time from 7 days (which is required for complete closure of control hTECs exposed to DMSO) to only 4 days (when hTEC
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br Acknowledgements This work was
2024-01-05
Acknowledgements This work was supported by grants from the Program for Changjiang Scholars and Innovative Research Team in University (IRT_14R28), the National Basic Research Program of China (973) (Grant No.: 2013CB733602), the Major Research Plan of the National Natural Science Foundation of C
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α-Bungarotoxin br Colabeling evidence for ACh and GABA
2024-01-05
Colabeling evidence for ACh and GABA cotransmission Though functional demonstrations of ACh/GABA cotransmission remain largely limited to the retina and our recent analyses of cortex (Lee et al., 2010, Saunders et al., 2015a, Saunders et al., 2015b), evidence suggestive of ACh/GABA cotransmission
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Several tertiary prevention studies are
2024-01-05
Several tertiary prevention studies are currently underway examining the use of dutasteride for prostate cancer treatment: (1) during expectant management of prostate cancer, (2) after radical prostatectomy in men at high risk for relapse, and (3) in men with metastatic disease. The Reduction by Dut
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While the direct effects of ARI lead to
2024-01-05
While the direct effects of 5-ARI lead to a dramatic Caspase-3, human recombinant proteinase in serum DHT levels, other laboratory values are also affected by 5-ARI use. Serum testosterone elevations are known to occur with both finasteride and dutasteride use, but values will typically remain with
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Because antioxidants have a strong radical scavenging
2024-01-04
Because antioxidants have a strong radical scavenging efficiency, a mixture of H2O2 and antioxidants should exhibit a much weaker depolymerization process than H2O2 alone. Therefore, we expected the redox behavior of silver could be affected by the presence of the antioxidant. The schematic diagram
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Angiogenesis refers to the formation of
2024-01-04
Angiogenesis refers to the formation of new blood vessels from pre-existing vasculature [1]. Physiological angiogenesis is necessary for key processes such as wound healing, tissue regeneration and repair. In pathological conditions, including cardiovascular diseases, diabetes, cancer, and other pat
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Recent retrospective cohort studies have supported
2024-01-04
Recent retrospective cohort studies have supported these preclinical findings in animals indicating the correlation of AR activation with the induction of Celecoxib carcinogenesis. First, men with prostate cancer who underwent androgen deprivation therapy were shown to have a significantly lower ri
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