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Each of these substrate receptors belongs to a
2019-11-14
Each of these substrate receptors belongs to a multigene family with tens, if not hundreds of members in plants, and with in part overlapping and in part differential substrate specificities [4]. The complexity of the system is nicely illustrated by the F-box protein and auxin receptor TRANSPORT INH
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BQ-123 The present study was set to characterise
2019-11-14
The present study was set to characterise the DNMT gene orthologs and describe the expression patterns of these genes during seed development in natural diploid apomict B. divaricarpa and diploid sexual B. stricta. Material and methods Results The B. stricta genome v1.2, was sequenced and ass
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Resistance to SP is linked to point
2019-11-14
Resistance to SP is linked to point mutations that accumulate at several sites in the dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) NKH 477 of P. falciparum (Roper et al., 2003). These mutations have been identified in codons 16, 51, 59, 108, and 164 in the dhfr gene and codons
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br Experimental br Results and discussion br Conclusions In
2019-11-14
Experimental Results and discussion Conclusions In this work we presented the direct electrochemical behaviour of the Mo containing formate dehydrogenase, purified from D. desulfuricans, where the Mo centre redox features were observed. The results allowed to calculate the reduction potenti
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Endothelial dysfunction has been associated with
2019-11-14
Endothelial dysfunction has been associated with most of the established cardiovascular risk factors, such as hypercholesterolemia, hypertension, smoking, diabetes mellitus, a positive history of premature CAD and elevated L-745,870 trihydrochloride australia homocysteine 4, 26, 27. Endothelial dys
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When a hour delay period was
2019-11-14
When a 6-hour delay XL-888 was implemented for the WRAM, neither of the E2-treated groups (E2-only and E2 + Levo) differed in WMC errors between the postdelay trials and the baseline trials. This suggests that exogenous E2 treatment protected from a delay-induced impairment in performance on working
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The transcription factor CREB has been extensively studied
2019-11-14
The transcription factor CREB has been extensively studied for its role in hippocampus-dependent learning and memory (West et al., 2002, Lonze and Ginty, 2002). Previous research has demonstrated that the phosphorylation of CREB at Ser133, performed by the ERK1/2 signaling pathway, initiates a casca
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First of all it should be
2019-11-14
First of all, it should be emphasized that, although cPLA2α manifests a marked selectivity for phospholipids that contain AA at the sn-2 position, this does not mean in any way that, in cells, the enzyme cannot hydrolyze other fatty acyl residues to a significant extent even if this occurs at a lowe
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Captopril Our results showed that in elastase induced AAA TG
2019-11-14
Our results showed that in elastase-induced AAA, TGF-β neutralization finely tunes macrophage phenotype. Note that several studies have already addressed the role of M1 markers, such as IL-6 and IL-1β, or M2 markers, including IL-10 and TGF-β.4, 9, 10, 11 The expression and the role of ARG1 in AAA h
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br Experimental procedures br Acknowledgments br Introductio
2019-11-14
Experimental procedures Acknowledgments Introduction Receptor tyrosine kinases (RTKs) control many fundamental cellular processes, such as cell proliferation, differentiation, migration, and metabolism (Lemmon and Schlessinger, 2010). RTK activity is normally tightly controlled, and dysregu
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The attachment of ubiquitin to RTKs such
2019-11-14
The attachment of ubiquitin to RTKs, such as EGFR, mediates efficient delivery through the endosome-lysosome system for proteolysis. In this way, RTK degradation enables cessation of signal transduction. A recent siRNA screen identified a number of USPs that can significantly modulate EGFR levels an
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After crown formation root development begins via the intera
2019-11-14
After crown formation, root development begins via the interaction between the Hertwig root sheath (HERS) and the dental papilla, which differentiates into odontoblasts and forms dentin and pulp. HERS is associated with the number of roots and their morphology . The stem cells from the apical papill
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br Experimental Procedures br Author Contributions
2019-11-14
Experimental Procedures Author Contributions Acknowledgments We acknowledge Géraldine Le Goff and Mathieu Canales for blood sampling, Cécile Gameiro and Jean-Pierre Aubry for flow cytometry technical assistance, Giuseppe Pantaleo for support, and Britta Engelhardt, Gisella Puga-Young, Nicol
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In a study carried out by Aunis et al
2019-11-14
In a study carried out by Aunis et al. the properties of soluble DBH and membrane bound were examined [23]. The membrane bound enzyme was shown in Pyrene azide 3 to the soluble form to have thermal denaturation at higher temperatures of 43.5–44°C. Similar discontinuities in the Arrhenius plots were
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L-817,818 Epitope analyses of AT AA and ET AA indicate
2019-11-13
Epitope analyses of AT1-AA and ET-AA indicate that the L-817,818 of both autoantibodies are located at the second extracelluar loop of both receptors. The specific epitopes for both autoantibodies are similar to what was reported previously in a cohort of patients from Brazil [6] and for AT1-AA also
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